They’ll become available once you finish a side quest called Turn and Face the Strange. You’ll need to invest skill points and mutagens to research them. When you go into the menu, you’ll see only three available at the beginning. Blood & Wine MutationsMutations are divided into three groups – combat, alchemy and magic, although some are hybrids. If some other stuff in the game is giving you headaches, we strongly recommend browsing through our Witcher 3 Blood and Wine Walkthrough & Guides.
This guide will show you how Witcher 3 mutations work, how to research them and unlock new skill slots.
You’ll need to research them first, and investing in them will unlock new ability slots.
